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Progression from intermediate age-related macular degeneration to neovascular disease. Baseline color fundus photograph (A) and optical coherence tomography (OCT) (C) show confluent drusen and drusenoid retinal pigment epithelial detachment that evolve to neovascular disease (NV) (B, D). Pigmentary clumping was evident from baseline through progression to NV (arrows in A, B, D).
