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. 2017 Jul 14;48:39. doi: 10.1186/s13567-017-0443-4

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The S. suis serotype 9 (S9) AgI/II, but not that of the serotype 2 (S2), is implicated in bacterial self-aggregation and biofilm formation. The role of the S. suis AgI/II was evaluated with regards to cell-to-cell aggregation in fluid phase (A) and biofilm formation capacity in the presence of porcine fibrinogen (B) after 24 h of incubation at 37 °C. Data represent the mean ± SEM from at least three independent experiments. **(p < 0.01) and ***(p < 0.001) indicate a significant difference between the S. suis S9 wild-type or complemented strain (S9CΔagI/II) and agI/II-deficient mutant (S9ΔagI/II).