Table 4.
Univariate and multivariate logistic regression analysis for infectious complications
| Elements | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p Value | OR | 95% CI | p Value | |
| Age | 1.038 | 1.001–1.077 | 0.041 | 1.025 | 0.969–1.084 | 0.386 |
| APACHE II score | 1.249 | 1.097–1.422 | 0.001 | 1.305 | 1.079–1.578 | 0.006 |
| Lymphocyte count on day 1 × 109/L | 0.821 | 0.691–0.975 | 0.025 | 0.956 | 0.697–0.761 | 0.691 |
| Percentage of HLA-DR expression on CD14+ monocytes on day 1 | 0.959 | 0.923–0.996 | 0.031 | 0.923 | 0.869–0.981 | 0.01 |
| Percentage of PD-1 expression on CD4+ lymphocytes on day 1 | 1.070 | 1.006–1.137 | 0.031 | 1.046 | 0.956–1.143 | 0.327 |
| Percentage of PD-L1 expression on CD14+ monocytes on day 1 | 1.075 | 1.016–1.138 | 0.013 | 1.098 | 1.005–1.200 | 0.036 |
Abbreviations: APACHE Acute Physiology and Chronic Health Evaluation, HLA-DR Human leukocyte antigen-DR, PD-1 Programmed cell death receptor 1, PD-L1 Programmed cell death receptor ligand 1