Table 2.

Plasma arginine derivatives

	Controls	Surgical trauma	Sepsis	Septic shock	P value for trenda
L-arginine (μmol/L)	35.0 (21.6–52.9)	19.8 (13.0–48.5)	29.4 (14.8–42.5)	24.4 (6.2–49.3)	ns
Homoarginine (μmol/L)	1.89 (1.30–2.29)	1.06 (0.67–1.67)	0.92 (0.59–1.36)	0.79 (0.36–1.44)	<0.001
ADMA (μmol/L)	0.57 (0.46–0.65)	0.53 (0.44–0.65)	0.80 (0.56–0.93)	0.89 (0.56–1.39)	<0.001

Data are presented as median (IQR, interquartile range). ADMA asymmetric dimethylarginine, ns not significant

^aNon-parametric Kruskal-Wallis test for trend analysis in controls vs. patient groups