Table 2.
Associations between central lymph node metastasis (CLNM) and clinicopathological characteristics in solitary papillary thyroid microcarcinomas
| Parameter | CLNM− | CLNM+ | P value |
|---|---|---|---|
| (n = 792) | (n = 300) | ||
| Age (years) | |||
| <45 | 321 (62.6%) | 192 (37.4%) | |
| ≥45 | 471 (81.3%) | 108 (18.7%) | <0.001 |
| Sex | |||
| Male | 111 (57.8%) | 81 (42.2%) | |
| Female | 681 (75.7%) | 29 (24.3%) | <0.001 |
| Size (cm) | |||
| ≤0.5 | 484 (80.4%) | 118 (19.6%) | |
| >0.5 | 308 (62.9%) | 182 (37.1%) | <0.001 |
| Tumor extent | |||
| Within capsule | 533 (76.3%) | 166 (23.7%) | |
| Capsule invasion | 231 (69.0%) | 104 (31.0%) | |
| Extrathyroidal extension | 28 (48.3%) | 30 (51.7%) | <0.001 |
| Lymphocytic thyroiditis | |||
| Present | 104 (80.6%) | 25 (19.4%) | |
| Absent | 688 (71.4%) | 275 (28.6%) | 0.028 |
| Subtype | |||
| Classic | 783 (69.2%) | 296 (30.8%) | |
| Follicular | 9 (69.2%) | 4 (30.8%) | 0.789 |