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. 2017 Jul 17;12(7):e0181085. doi: 10.1371/journal.pone.0181085

Fig 9. ERK activation is required to mediate the effects of stiffness on RPTEC proliferation.

Fig 9

RPTECs were cultured on hydrogel substrates in the presence of 50 μM PD98059 or DMSO vehicle (exchanged daily) for 4 d. DAPI stained nuclei were quantified and normalized to RPTEC density on glass with vehicle. *: p < 0.05 relative to glass; ‡: p < 0.05 relative to 20 kPa; #: p < 0.05 relative to vehicle control. There were no statistical differences in cell density between conditions treated with PD98059.