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. Author manuscript; available in PMC: 2017 Jul 17.
Published in final edited form as: Nature. 2016 Dec 14;541(7635):52–57. doi: 10.1038/nature20775

Extended Data Figure 2. Cryo-EM structure of EDTA aplysia Slo1.

Extended Data Figure 2

a, Cryo-EM density maps of two conformations of EDTA Slo1 aligned by their gating rings. The density slices correspond to the regions between the dashed lines in the TMD and the gating ring. b, Wire diagrams of EDTA Slo1 in four different conformations. c, Superposition of two EDTA Slo1 conformations aligned by their pore helices and selectivity filters. d, Superposition of the inner (S6) helices of the four EDTA Slo1 states aligned by their pore helices and selectivity filters. e, Plot of pore diameter along the length of the pore in the TMD for the four EDTA and the open Slo1 states.