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. 2017;38(2):147–161.

Table 2.

Lipogenic Enzymes Regulated by SREBP-1c

Enzyme Abbreviation Function
Fatty Acid Synthase FAS Synthesizes fatty acids from acetyl coenzyme A (CoA) and palmitate
Acyl CoA Carboxylase ACC Synthesizes malonyl CoA from acetyl CoA
ATP Citrate Lyase ACL Converts citrate and CoA to acetyl CoA
Stearoyl CoA Desaturase SCD Synthesizes unsaturated fatty acids (oleate) from saturated fatty acids (stearate)
Malic Enzyme ME Generates reducing equivalents (NADPH) for triglyceride synthesis