Table 1.

INTERHEART Data, Patterns of Alcohol Use, and Odds Ratio (OR) for Myocardial Infarction (MI).

Pattern of Alcohol Use	OR (95%) for MI	p value
Any alcohol use within 12 months
Unadjusted	0.92 (0.87–0.96)	<0.001
Adjusted (model 1)	0.81 (0.76–0.87)	<0.001
Adjusted (model 2)	0.87 (0.80–0.94)	0.001
Pooled*	0.84 (0.71–0.99)	0.04
Any alcohol use and risk of MI in subsequent 24 hours	1.0 (0.9–1.2)	0.70
≥ 6 Drinks and risk of MI in subsequent 24 hours	1.4 (1.1–1.9)	0.01

NOTE: Model 1 was adjusted for age (categorized as <45, 45–65, and >65 years), gender, geographic region, Dietary Risk Score, exercise, smoking, marital status, employment, education level, depression, stress at work or at home, financial stress, body mass index (BMI), and waist-to-hip ratio. Model 2 was adjusted as for Model 1 and for serum ratio of apolipoprotein B to apolipoprotein; total cholesterol, high-density lipoprotein, low-density lipoprotein, and triglyceride concentrations; and history of hypertension or diabetes mellitus. CI = confidence interval; MI = myocardial infarction; OR = odds ratio.

^*P ooled effect estimates from conditional logistic regression were stratified by geographic region and adjusted for Dietary Risk score, exercise, smoking, marital status, employment, education level, depression, stress at work or at home, financial stress, BMI, and waist-to-hip ratio.

SOURCE: Used with permission from Leong et al. 2014.