Table 3.

Effect of Minimal Residual Disease on Mortality and Risk of Relapse, According to Donor Group.^*

Donor Group	Overall Mortality		Risk of Relapse
	Hazard Ratio (95% CI)	P Value	Hazard Ratio (95% CI)	P Value
HLA-matched group	2.34 (1.59–3.45)	<0.001	3.23 (2.01–5.19)	<0.001
HLA-mismatched group	2.33 (1.32–4.09)	0.003	3.37 (1.39–8.15)	0.007
Cord-blood group	1.09 (0.57–2.08)	0.80	1.43 (0.58–3.57)	0.44

^*The hazard ratio represents the adjusted risk of treatment failure among patients with minimal residual disease as compared with those without minimal residual disease. The analyses were adjusted for age (as a cubic polynomial), severity of disease, year of transplantation (as a continuous linear variable), and use or nonuse of high-dose total-body irradiation. Data on minimal residual disease status were missing for 3 patients in the cord-blood group, for 13 in the HLA-matched group, and for 8 in the HLA-mismatched group.