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. Author manuscript; available in PMC: 2018 Apr 7.
Published in final edited form as: J Am Chem Soc. 2016 Oct 13;138(42):14092–14099. doi: 10.1021/jacs.6b08942

Table 4.

Meta-Amination of Phenolsa,b

graphic file with name nihms870377f7.jpg
a

Reaction conditions: 5 (0.1 mmol), 2 (0.15 mmol), Pd(OAc)2 (2.2 mg, 10 mol%), L28 (10 mol%), NBE-CO2Me (21.4 mg, 1.5 equiv.), AgOAc (33.4 mg, 2.0 equiv.), CH2Cl2 (1.0 mL), 100 °C, Air, 24 h.

b

Isolated yield.

c

The selectivity of mono- and di-products was determined by 1H NMR.