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Dioscin activates Sirt1 levels in vitro and in vivo. (A) Effects of dioscin on Sirt1 levels based on immunofluorescence staining in NRK‐52E and HK‐2 cells (200× magnification). (B) Effects of dioscin on Sirt1 levels based on immunofluorescence staining in renal tissues from rats and mice (200× magnification). Data are presented as the mean ± SD (n = 5). # P < 0.05, significantly different from control group; *P < 0.05, significantly different from CDDP groups.
