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. 2017 Jul 5;174(15):2512–2527. doi: 10.1111/bph.13862

Figure 6.

Figure 6

Dioscin suppresses inflammation caused by CDDP in vitro and in vivo. (A) Effects of dioscin on the protein levels of AP‐1, COX‐2, IκB‐α degradation, HMGB1 and acetylated NF‐κB in vitro and in vivo. (B) Effects of dioscin on the mRNA levels of IL‐1β, IL‐6 and TNF‐α in vitro and in vivo. Data are presented as the mean ± SD (n = 5). # P < 0.05, significantly different from control group; *P < 0.05, significantly different from CDDP groups.