Table 1.

Chronic effects of Bou on metabolic parameters in mice

	CH	CH‐Bou	HF	HF‐Bou
Plasma FFA (mM)	1.1 ± 0.06	0.9 ± 0.03	2.1 ± 0.15*	1.3 ± 0.16‡
Plasma TG (mM)	1.2 ± 0.37	1.1 ± 0.22	2.5 ± 0.2*	1.5 ± 0.3‡
Plasma CHO (mM)	2.1 ± 0.1	1.6 ± 0.1*	2.2 ± 0.2	2.0 ± 0.4
Plasma HDL (mM)	1.7 ± 0.1	1.9 ± 0.3	1.47 ± 0.14*	1.6 ± 0.2
Plasma LDL (mM)	0.15 ± 0.02	0.14 ± 0.03	0.3 ± 0.04*	0.2 ± 0.04
Plasma glucose (mM)	4.4 ± 0.3	4.7 ± 0.5	10.8 ± 1.4*	6.8 ± 1.4‡
Plasma insulin (ng·mL−1)	2.2 ± 0.3	2.0 ± 0.4	3.6 ± 0.2*	2.7 ± 0.4‡
Plasma AST (U·L−1)	101 ± 13	110 ± 11	135 ± 6*	125 ± 8
Plasma ALT (U·L−1)	25.8 ± 2.9	25.90 ± 5.2	32.2 ± 5.3	28.8 ± 6.9
Plasma ALP (U·L−1)	49.7 ± 7.0	42.2 ± 4.3	62.8 ± 8.3	54.4 ± 3.3‡
Plasma UREA (mM)	12.7 ± 1.2	11.2 ± 1.7	13.1 ± 2.2	13.0 ± 2.7
Plasma BUN (mM)	5.3 ± 0.6	4.8 ± 0.9	6.9 ± 1.5	6.1 ± 0.7
Plasma CR (μM)	78.8 ± 7.9	47.5 ± 7.9	99.8 ± 6.1	74.6 ± 11.6‡
Plasma TBIL (mM)	1.2 ± 0.3	1.2 ± 0.5	1.1 ± 0.4	1.3 ± 0.3
Plasma TP (mM)	49.6 ± 1.8	52.1 ± 4.2	62.9 ± 4.4	54.2 ± 5.2
Plasma ALB (mM)	19.7 ± 0.6	19.7 ± 1.5	19.1 ± 1.8	18.5 ± 1.6
Liver weight (g)	1.5 ± 0.5	1.5 ± 0.2	1.9 ± 0.2*	1.6 ± 0.2‡
eWAT (g)	0.32 ± 0.05	0.27 ± 0.05	0.82 ± 0.17	0.51 ± 0.15
sWAT (g)	0.24 ± 0.03	0.22 ± 0.08	0.60 ± 0.09	0.34 ± 0.06
Total fat mass (g)	0.56 ± 0.005	0.49 ± 0.03	1.42 ± 0.13*	0.85 ± 0.09‡

Plasma samples were collected after 5 weeks of treatment with Bou and analysed by automatic biochemical analyser.

^* P < 0.05 compared with CH group.

^‡ P < 0.05 compared with HF mice (n = 8 per group).

TC, total cholesterol; LDL‐c, LDL‐cholesterol; HDL‐c, HDL‐cholesterol; ALP, alkaline phosphatase; ALT, glutamic‐pyruvic transaminase; AST, aspartate aminotransferase; TP, total protein; BUN, blood urea nitrogen; CR, creatinine; TBIL, total bilirubin; ALB, albumin; FFA, free fatty acid; CHO, carbohydrate.