Table 2.
Sinus rhythm (n = 4) | cAVB (n = 9) | cAVB (n = 9) | ||||
---|---|---|---|---|---|---|
Baseline | PA‐6 | Baseline | PA‐6 | Baseline | Dofetilide | |
RRa | 601 ± 54 | 605 ± 55 | 1000 | 1000 | 1000 | 1000 |
PQb | 129 ± 20 | 125 ± 18 | n.a. | n.a. | n.a. | n.a. |
QRS | 75 ± 5 | 75 ± 4 | 117 ± 9 | 118 ± 8 | 115 ± 10 | 115 ± 11 |
QTc | 306 ± 21 | 326 ± 16 | 384 ± 40 | 465 ± 89* | 381 ± 26 | 600 ± 33* |
STV | 0.29 ± 0.02 | 0.39 ± 0.17 | 0.60 ± 0.22 | 1.20 ± 0.68 | 0.77 ± 0.23 | 1.82 ± 0.88 |
LVMAPD80 | 197 ± 21 | 216 ± 28 | 236 ± 20 | 285 ± 52* | 249 ± 18 | 400 ± 64* |
cAVB dogs are paced from the right ventricular apex at 1 Hz;
cAVB dog has per definition no PQ conduction;
P < 0.05 versus baseline.