Table 2.

Electrophysiological parameters (in ms) in sinus rhythm and cAVB dogs in control conditions and upon drug application

	Sinus rhythm (n = 4)		cAVB (n = 9)		cAVB (n = 9)
	Baseline	PA‐6	Baseline	PA‐6	Baseline	Dofetilide
RRa	601 ± 54	605 ± 55	1000	1000	1000	1000
PQb	129 ± 20	125 ± 18	n.a.	n.a.	n.a.	n.a.
QRS	75 ± 5	75 ± 4	117 ± 9	118 ± 8	115 ± 10	115 ± 11
QTc	306 ± 21	326 ± 16	384 ± 40	465 ± 89*	381 ± 26	600 ± 33*
STV	0.29 ± 0.02	0.39 ± 0.17	0.60 ± 0.22	1.20 ± 0.68	0.77 ± 0.23	1.82 ± 0.88
LVMAPD80	197 ± 21	216 ± 28	236 ± 20	285 ± 52*	249 ± 18	400 ± 64*

^a cAVB dogs are paced from the right ventricular apex at 1 Hz;

^b cAVB dog has per definition no PQ conduction;

^* P < 0.05 versus baseline.