Table 3.

Protective efficacy of common antigen EaGAPDH against challenge with E. tenella, E. acervulina, E. maxima, and mixed oocysts of the three Eimeria species.

Group	Challenge with Eimeria spp.	Average body weightgain (g)	Relative body weight gain (%)	Mean lesionscores	Oocyst decrease ratio (%)	ACI
pVAX-EaGAPDH	E. tenella	48.28 ± 11.26b	79.54	0.53 ± 0.53b	85.98	169.24
pVAX-EmGAPDH	E. tenella	49.16 ± 12.23b	80.24	0.67 ± 0.72b	82.28	168.54
pVAX1 control	E. tenella	35.26 ± 9.89c	58.00	3.59 ± 0.51c	5.03	112.1
Challenged control	E. tenella	32.58 ± 10.29c	53.11	3.78 ± 0.67c	0.00	105.41
Unchallenged control∗	PBS	61.30 ± 9.29a	100	0 ± 0a	100	200
pVAX-EaGAPDH	E. acervulina	47.95 ± 8.47bc	79.57	1.35 ± 0.67b	58.59	165.07
pVAX-EmGAPDH	E. acervulina	52.11 ± 10.28b	87.07	1.46 ± 0.86b	55.21	171.47
pVAX1 control	E. acervulina	38.41 ± 10.93c	63.20	3.01 ± 0.81c	7.67	93.1
Challenged control	E. acervulina	37.38 ± 10.27c	62.37	3.26 ± 0.67c	0.00	89.77
Unchallenged control∗	PBS	61.30 ± 9.29a	100	0 ± 0a	100	200
pVAX-EaGAPDH	E. maxima	49.10 ± 9.26b	82.37	1.62 ± 0.75bc	44.14	165.17
pVAX-EmGAPDH	E. maxima	51.03 ± 12.45b	85.01	1.32 ± 0.81b	54.48	170.81
pVAX1 control	E. maxima	35.39 ± 11.52c	58.62	2.56 ± 0.71c	11.72	93.02
Challenged control	E. maxima	35.18 ± 12.21c	57.18	2.90 ± 0.67c	0.00	88.18
Unchallenged control∗	PBS	61.30 ± 9.29a	100	0 ± 0a	100	200
pVAX-EaGAPDH	Mixed oocysts	45.68 ± 9.76b	74.38	0.47 ± 0.61b	47.75	164.68
pVAX-EmGAPDH	Mixed oocysts	48.68 ± 10.21b	79.80	0.75 ± 0.54b	56.18	171.1
pVAX1 control	Mixed oocysts	35.10 ± 10.81c	57.57	3.58 ± 0.61c	–1.69	111.77
Challenged control	Mixed oocysts	33.08 ± 11.09c	53.77	3.70 ± 0.57c	0.00	106.77
Unchallenged control∗	PBS	61.30 ± 9.29a	100	0 ± 0a	100	200

Significant difference (p < 0.05) between numbers with different letters. No significant difference (p > 0.05) between numbers with the same letter; ^∗unchallenged control was shared among the groups challenged with different Eimeria species; mixed oocysts: mixed oocysts of E. tenella, E. acervuline, and E. maxima.