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. 2017 Jul 18;8:473. doi: 10.3389/fphar.2017.00473

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Copyright © 2017 Ma, Zhu, Liu, Wang, Yang, Chen and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of lovastatin on oxidative stress in kidney. (A) DHE staining in kidney sections in each group (B,C) The product of lipid peroxidation (MDA) and superoxide dismutase (SOD) in each group. (D) Immunostaining for NOX4. (E) Western blot of NOX4 proteins in different groups. NC, normal control group; DM, diabetic group; DM +Lovastatin, lovastatin-treated diabetic group. ^*P < 0.05 between the NC and the DM groups; ^#P < 0.05 between the DM and the DM + Lovastatin groups.