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. 2017 Jul 18;8:1272. doi: 10.3389/fmicb.2017.01272

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Copyright © 2017 Utturkar, Klingeman, Hurt and Brown.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary of biological features with potential to interfere with the assembly process. (A) Presence of active transposon elements in strain JBW45 (B) repetitive transposon sequences at the contig terminus region of B. cellulosolvens (C) large sequence duplications in C. pasteurianum (D) presence of megaplsmids in stain KO116 (E) genome duplication assembled as spurious contig in C. thermocellum LQRI (F) multiple copies of rRNA operons in C. paradoxum JW-YL-7. The figures are illustration only and not drawn to scale.