FIGURE 3.

Preventive effects of oral DCH on brain injury after focal cerebral ischemia in mice. DCH (5, 10, or 20 g/kg) and FA (100 mg/kg) were orally administered for five consecutive days before inducing brain ischemia. The neurological deficit score (A), infarct volume (B), and ipsilateral edema (C) were determined. (D), Representative brain coronal sections (2 mm thick) stained with 2% TTC. Typical infarct regions are indicated in white and normal regions are indicated in red. Data are represented as mean ± SEM, n = 10, ^∗p < 0.05, ^∗∗p < 0.01 versus vehicle group.