Table 4.
Diagnostic test indices of GGT for predicting premature coronary artery disease in the study population and men and women separately
Population | GGT cut-off | AUC | 95% CI | Sensitivity | Specificity | PPV | NPV | Diagnostic accuracy | P-value* |
---|---|---|---|---|---|---|---|---|---|
All patients | 22.5 | 80.9 | 76.5–85.3 | 80.1 | 70.2 | 71.3 | 79.3 | 74.9 | <0.001 |
Men | 35.5 | 77.1 | 76.5–85.3 | 62.4 | 86.5 | 82.1 | 67 | 73.3 | <0.001 |
Women | 22.5 | 83.2 | 77.0–88.2 | 79.1 | 80 | 75.8 | 82.9 | 79.6 | <0.001 |
AUC area under the ROC curve, CI confidence interval, GGT gamma-glutamyltransferase, NPV negative predictive value, PPV positive predictive value
*p < 0.05 was considered statistically significant