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. 2017 Jul 17;7:5555. doi: 10.1038/s41598-017-05621-5

Figure 5.

Figure 5

MIC-fold change for each antibiotic tested between isolates mutated or not mutated in a specific gene. To evaluate the implication of the presence of mutations in the main genes possibly related with antibiotic resistance the median MIC for both groups were calculated and compared, results are expressed in MIC-fold change. PA2489, mexW, oprF, parE and nfxB were excluded since the number of mutated isolates were < 3. Some genes were grouped (e.g. ampD and dacB (PBP4) or nalD and mexR) according to their well-established effects on resistance (e.g. AmpC or MexAB-OprM overexpression, respectively).