Table 5.
Significantly enriched biological processes and pathways affected by subtype specific alternative exon usage.
| ER− HER2− | ER+ HER2− | HER2+ | ||||||
|---|---|---|---|---|---|---|---|---|
| Biological Process | Name | p-value (FDR B&H) | Biological Process | Name | p-value (FDR B&H) | Biological Process | Name | p-value (FDR B&H) |
| GO:0007049 | cell cycle | 1.35E-06 | GO:0051056 | regulation of small GTPase mediated signal transduction | 3.12E-09 | GO:0022008 | neurogenesis | 1.09E-07 |
| GO:0000278 | mitotic cell cycle | 7.38E-06 | GO:0007265 | Ras protein signal transduction | 2.25E-08 | GO:0016568 | chromatin modification | 1.27E-07 |
| GO:0030056 | hemidesmo some | 2.32E-05 | GO:0043087 | regulation of GTPase activity | 2.37E-07 | GO:0030182 | neuron differentiation | 1.81E-06 |
| GO:0008305 | integrin complex | 1.89E-04 | GO:0007266 | Rho protein signal transduction | 1.73E-06 | GO:0006325 | chromatin organization | 7.85E-06 |