Table 1.
Description | Component metabolites | Eigenvalue | Percentage of variance | Cumulative percentage of variance | Obesity | Percentage of variance explaining obesity | ||
---|---|---|---|---|---|---|---|---|
OR | P value | |||||||
PC1 | Miscellaneus | Citrulline, Glycine, Alanine, Leucine + Isoleucine, Methionine, Phenylalanine, Valine, Succinylacetone, Propionylcarnitine C3, Butyryl + isobutyrylcarnitine C4, Tiglylcarnitine C5:1, Hexanoylcarnitine C6, Octanoylcarnitine C8, Octenoylcarnitine C8:1, Hexadecenoylcarnitine C16:1, Hydroxyhexadecenoylcarnitine C16:1-OH, Hydroxypalmitoylcarnitine C16-OH, Decanoylcarnitine C10, Decenoylcarnitine C10:1, Decadienoylcarnitine C10:2, Dodecanoylcarnitine C12, Dodecenoylcarnitine C12:1, Tetradecanoylcarnitine C14, Tetradecenoylcarnitine C14:1, Tetradecadienoylcarnitine C14:2, 3-hydroxytetradecenoylcarnitine C14:OH, Stearylcarnitine C18, Linoleylcarnitine C18:2, Hydroxybutyrylcarnitine C4OH + Malonylcarnitine C3DC, Hydroxyisovalerylcarnitine C5OH + Succinyl + methylmalonylcarnitine C4DC | 14.39 | 33.46 | 33.46 | 1.04 (1.00–1.07) | 0.03 | 1.03 |
PC2 | Amino acids | Arginine, Leucine + Isoleucine, Phenylalanine, Tyrosine, Valine, Proline | 5.20 | 12.09 | 45.55 | 1.57 (1.45–1.69) | 3.84 × 10 −31 | 15.28 |
PC3 | Acycarnitines | Acetylcarnitine C2, Palmitoylcarnitine C16, Stearylcarnitine C18 | 3.23 | 7.51 | 53.06 | 1.21 (1.11–1.33) | 4.46 × 10 −5 | 0.88 |
PC4 | Shortchain acylcarnitines | Acetylcarnitine C2, Propionylcarnitine C3 | 2.49 | 5.78 | 58.84 | 0.97 (0.89–1.04) | 0.409 | 0.03 |
PC5 | Medium chain acylcarnitines | Methylglutarylcarnitine C6DC, Dodecanoylacylcarnitine C12 | 2.13 | 4.95 | 63.79 | 0.53 (0.47–0.60) | 7.63 × 10 −25 | 6.52 |
PC6 | Miscellaneus | Ornithine, Octenoylcarnitine C8:1 | 1.37 | 3.18 | 66.98 | 0.93 (0.84–1.03) | 0.19 | 0.30 |
The logistic regression model was adjusted for gender and age.Significant P-values are shown in bold.