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. 2017 Jul 17;7:5607. doi: 10.1038/s41598-017-05765-4

Table 1.

Principal component analysis of 42 metabolites and associations of clusters with obesity in a case-control cohort of Mexican school-age children.

Description Component metabolites Eigenvalue Percentage of variance Cumulative percentage of variance Obesity Percentage of variance explaining obesity
OR P value
PC1 Miscellaneus Citrulline, Glycine, Alanine, Leucine + Isoleucine, Methionine, Phenylalanine, Valine, Succinylacetone, Propionylcarnitine C3, Butyryl + isobutyrylcarnitine C4, Tiglylcarnitine C5:1, Hexanoylcarnitine C6, Octanoylcarnitine C8, Octenoylcarnitine C8:1, Hexadecenoylcarnitine C16:1, Hydroxyhexadecenoylcarnitine C16:1-OH, Hydroxypalmitoylcarnitine C16-OH, Decanoylcarnitine C10, Decenoylcarnitine C10:1, Decadienoylcarnitine C10:2, Dodecanoylcarnitine C12, Dodecenoylcarnitine C12:1, Tetradecanoylcarnitine C14, Tetradecenoylcarnitine C14:1, Tetradecadienoylcarnitine C14:2, 3-hydroxytetradecenoylcarnitine C14:OH, Stearylcarnitine C18, Linoleylcarnitine C18:2, Hydroxybutyrylcarnitine C4OH + Malonylcarnitine C3DC, Hydroxyisovalerylcarnitine C5OH + Succinyl + methylmalonylcarnitine C4DC 14.39 33.46 33.46 1.04 (1.00–1.07) 0.03 1.03
PC2 Amino acids Arginine, Leucine + Isoleucine, Phenylalanine, Tyrosine, Valine, Proline 5.20 12.09 45.55 1.57 (1.45–1.69) 3.84 × 10 −31 15.28
PC3 Acycarnitines Acetylcarnitine C2, Palmitoylcarnitine C16, Stearylcarnitine C18 3.23 7.51 53.06 1.21 (1.11–1.33) 4.46 × 10 −5 0.88
PC4 Shortchain acylcarnitines Acetylcarnitine C2, Propionylcarnitine C3 2.49 5.78 58.84 0.97 (0.89–1.04) 0.409 0.03
PC5 Medium chain acylcarnitines Methylglutarylcarnitine C6DC, Dodecanoylacylcarnitine C12 2.13 4.95 63.79 0.53 (0.47–0.60) 7.63 × 10 −25 6.52
PC6 Miscellaneus Ornithine, Octenoylcarnitine C8:1 1.37 3.18 66.98 0.93 (0.84–1.03) 0.19 0.30

The logistic regression model was adjusted for gender and age.Significant P-values are shown in bold.