Table 4.

Factors associated with the presence of type 2 diabetes mellitus in clinically-defined heterozygous familial hypercholesterolemia patients (≥6 DLCN points).

	Standard coeff. (β)	Exp (B)	95% CI	P	R2
Sex, male	0.649	1.913	1.204–3.040	0.006	0.261
Age, years	0.050	1.052	1.030–1.074	<0.001
BMI, kg/m2	0.021	1.021	1.007–1.035	0.004
Hypertension, yes	1.522	4.582	2.834–7.407	<0.001
Triglycerides, mg/dL	0.002	1.002	1.001–1.003	0.001
Statin therapy, years	0.031	1.031	1.003–1.060	0.03

DLCN denotes Dutch Lipid Clinic Network; BMI, body mass index.

Independent variables included in the model: sex, age, BMI, smoking status, hypertension, tendon xanthomas, baseline LDL and HDL cholesterol and triglyceride concentrations, genetic diagnosis and statin therapy duration.