Table 6.
Effect of phenotype severity in heterozygous familial hypercholesterolemia on type 2 diabetes prevalence.
Comparison | All | HeFH with LDL <250 mg/dL | HeFH with LDL ≥250 mg/dL | HeFH with >8 points |
---|---|---|---|---|
Odds ratio (95% CI) Unadjusted | 0.821 (0.429–1.572) | 0.736 (0.287–1.887) | 2.384 (0.557–10.207) | 0.707 (0.294–1.696) |
Odds ratio (95% CI) Adjusted* | 0.954 (0.488–1.866) | 1.386 (0.498–3.852) | 2.395 (0.549–10.444) | 0.747 (0.303–1.839) |
Odds ratio (95% CI) Adjusted† | 0.936 (0.478–1.835) | 1.388 (0.496–3.887) | 2.806 (0.631–12.478) | 0.735 (0.298–1.813) |
Odds ratio (95% CI) Adjusted‡ | 1.072 (0.533–2.155) | 1.474 (0.512–4.243) | 3.056 (0.670–13.930) | 0.877 (0.341–2.250) |
*Adjusted for age, sex and years of statin use.
†Adjusted for age, sex, years of statin use and body mass index.
‡Adjusted for age, sex, years of statin use, body mass index, triglycerides, and hypertension.