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. 2017 Jul 17;7:5594. doi: 10.1038/s41598-017-06052-y

Figure 1.

Figure 1

Betatrophin levels are only increased by insulin in different insulin resistant models. Western blot analysis of pAkt Ser473 before and after 10 min of 100 nM insulin stimulation in L02 for the control and the six IR models (A). Betatrophin protein (B) and relative mRNA (C) expression of control and six IR models. Betatrophin mRNA expression of control and cells treated with insulin combined another agent (D). The data represent mean ± SEM. **P < 0.01 vs. the CON. CON: control; PA: palmitic acid; DXM: dexamethasone; TNF-α: tumor necrosis factor-α; IL-1β: interleukin-1β; HG: high glucose; INS: insulin.