Table 1.

Strong correlation of mRNA expression of activin and TGF-β pathway members.

Activin pathway	TGF-β pathway	rho	p-value	FDR
INHBA	TGFB3	0.666491996	<1E-22	<1E-22
INHBA	TGFB1	0.615817318	<1E-22	<1E-22
ACVR1	TGFBR1	0.601597339	<1E-22	<1E-22
ACVR2A	TGFBR1	0.574281616	<1E-22	<1E-22
ACVR1	TGFB2	0.50233367	<1E-22	<1E-22
INHBA	TGFB2	0.488423405	<1E-22	<1E-22
ACVR1	TGFB3	0.416297434	1.20E-12	7.78E-12
ACVR1	TGFBR2	0.345959021	6.60E-09	3.53E-08
INHBA	TGFBR1	0.335048949	2.04E-08	1.03E-07
ACVR2B	TGFBR2	0.3134617	1.68E-07	6.95E-07
ACVR2A	TGFBR2	0.300971359	5.30E-07	1.93E-06
ACVR1B	TGFBR2	0.294959388	9.05E-07	3.17E-06
ACVR2A	TGFB2	0.293090745	1.07E-06	3.59E-06

Activin and TGF-β ligands, receptor and downstream SMAD molecules were interrogated for correlation using Pearson’s correlation coefficient (rho). The p value of the correlation and the false discovery rate (FDR) are included.