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. 2017 Jul 17;7:5604. doi: 10.1038/s41598-017-05515-6

Table 1.

Metabolites described for antibiotic producing bacteria associated to the fungus-growing ants.

Fungus growing ants species Bacteria Bacterial activity Compounds isolated Compounds activity Reference
Apterostigma dentigerum Pseudonocardia spp. Escovopsis sp. dentigerumycin Escovopsis sp. 24
Pseudonocardia sp. Not reported selvamicin Candida albicans, Saccharomyces cerevisiae, Aspergillus fumigatus, and Trichoderma harzianum 33
Pseudonocardia sp. EC080529-01 Not reported 6-deoxy-8-O-methylrabelomycin Bacillus subtilis 3610 and Plasmodium berghei 23
X-14881 E (8-O-methyltetrangulol)
pseudonocardones A Inactive for test organism
pseudonocardones B
pseudonocardones C
A. octospinosus Pseudonocardia sp. Candida albicans and E. weberi nystatin P1 Not tested 26
Streptomyces sp. E. weberi candicidin D E. weberi 26, 27, 32, 34
Streptomyces sp. Streptomyces sp. Av25_2 Not reported actinomycin D B. subtilis
Acromyrmex sp. Streptomyces sp. Av25_2 Not reported actinomycin X2 B. subtilis 34
Streptomyces sp. Av25_3 Not reported valinomycin B. subtilis
Streptomyces sp. Ao10 E. weberi antimycin A1 E. weberi
antimycin A2
antimycin A3
antimycin A3
Trachymyrmex sp. Streptomyces sp. TD025. Five Candida species urauchimycin A Four Candida species 35
urauchimycin B Six Candida species

The table summarizes compounds that are produced by the bacteria associated with fungus growing ant’s species pointing out the activity against the fungal pathogen, Escovopsis.