Table 3.

Outcomes of volume replacement and radiation therapy

Study	Patients receiving ART (%)	ART dose-fractionation (Gy)	Patients receiving boost RT (%)	Boost RT dose-fractionation (Gy)	Patient rating on cosmesis	Professional rating on cosmesis	Local recurrence (%)	Distant recurrence (%)	Mortality (%)	Mean follow-up (mo, range)
Lee et al, 201462	64.3	---	---	---	82.3% satisfaction (mean score, >4)	Mean 4.13	---	---	---	11.3 (4-23)
Gendy et al, 200363	75.5	50 Gy in 25 fx over 5 wk	---	---	83.5% average satisfaction	3.8	4.1	---	---	53 (7-102)
Losken et al, 200464	84.6	---	---	---	---	---	5.1	10.3	5.1	44 (3-78)
Bogusevicius et al, 201456	100	Maximum 50 (in 25 fx)	0	0	92.3% excellent/good	87.2% excellent/good	10	38.3	23.3	86
Down et al, 201369	---	---	---	---	---	---	0	---	---	29.3
Kronowitz et al, 200629	100	Minimum 50	100	10-15	---	33% excellent/good (VR)	2	---	---	29
Tenofsky et al, 201457	93.1	---	---	---	86.2% favorable	---	0	---	---	24.6 (2.9-44.7)
Hamdi, 201370	---	---	---	---	---	---	1.7	---	---	48 (6-120)
Veiga et al, 201141	93.3	---	---	---	Mean 10 at 12 mo	Mean 9.25 at 12 mo	1	---	---	---
Munhoz et al, 200973	100	Daily fx dosing up to total 45-50	100	10	---	---	5.5	---	---	48 (10-108)
Munhoz et al, 200674	100	Daily fx dosing up to total 45-50	100	10	Good or very good 88.2%, satisfactory in 8.8%, poor in 12.9%		0	---	---	23

ART, adjuvant radiation therapy. See Tables 1 and 2 for other abbreviations.