Table 4.

Odds ratios and 95% confidence intervals for adiponectin, leptin, leptin/adiponectin ratio and resistin with dementia and MCI

	Dementia		AD		MD		VaD		MCI
	n = 205		n = 89		n = 69		n = 47		n = 113
	A	B	A	B	A	B	A	B	A	B
	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]	OR [95%CI]
Adiponectin (μg/mL)
1st Tertile (≤6.83)	1	1	1	1	1	1	1	1	1	1
2nd Tertile (6.84–11.70)	1.67 [1.25–2.25]	1.77 [1.26–2.48]	1.86 [1.30–2.67]	1.78 [1.17–2.72]	1.79 [1.21–2.64]	1.93 [1.17–3.20]	1.25 [0.81–1.92]	1.24 [0.74–2.07]	1.15 [0.82–1.60]	1.17 [0.80–1.70]
3rd Tertile (>11.70)	2.81 [1.55–5.07]	3.12 [1.60–6.17]	3.47 [1.69–7.11]	3.17 [1.36–7.41]	3.19 [1.47–6.95]	3.73 [1.37–10.22]	1.56 [0.66–3.70]	1.53 [0.55–4.28]	1.32 [0.68–2.56]	1.36 [0.64–2.89]
p	0.0006	0.001	0.0006	0.007	0.003	0.010	0.304	0.411	0.410	0.425
Leptin (ng/mL)
1st Tertile (≤5.89)	1	1	1	1	1	1	1	1	1	1
2nd Tertile (5.90–13.79)	0.90 [0.67–1.20]	0.78 [0.56–1.11]	0.87 [0.61–1.24]	0.68 [0.44–1.05]	0.90 [0.61–1.32]	0.99 [0.61–1.63]	0.92 [0.60–1.42]	0.92 [0.54–1.56]	1.64 [0.83–1.63]	1.22 [0.83–1.78]
3rd Tertile (>13.79)	0.80 [0.45–1.43]	0.61 [0.31–1.23]	0.76 [0.37–1.55]	0.46 [0.19–1.10]	0.81 [0.37–1.74]	0.98 [0.37–2.65]	0.85 [0.35–2.03]	0.85 [0.30–2.43]	1.36 [0.70–2.64]	1.48 [0.69–3.18]
p	0.452	0.165	0.442	0.079	0.583	0.976	0.709	0.756	0.369	0.310
L/A ratio
1st Tertile (≤0.579)	1	1	1	1	1	1	1	1	1	1
2nd Tertile (0.580–1.989)	0.74 [0.56–0.99]	0.67 [0.49–0.93]	0.67 [0.47–0.96]	0.59 [0.39–0.90]	0.70 [0.47–1.03]	0.74 [0.47–1.18]	0.93 [0.60–1.42]	0.98 [0.61–1.57]	1.006 [0.73–1.38]	1.001 [0.75–1.34]
3rd Tertile (>1.989)	0.56 [0.31–0.99]	0.45 [0.24–0.87]	0.45 [0.22–0.93]	0.35 [0.15–0.80]	0.49 [0.22–1.06]	0.56 [0.22–1.40]	0.86 [0.36–2.01]	0.95 [0.37–2.46]	1.013 [0.54–1.90]	1.004 [0.56–1.81]
p	0.045	0.017	0.029	0.013	0.069	0.209	0.720	0.923	0.969	0.990
Resistin (ng/mL)
1st Tertile (≤7.43)	1	1	1	1	1	1	1	1	1	1
2nd Tertile (7.44–10.07)	1.58 [1.17–2.13]	1.35 [0.97–1.88]	1.28 [0.90–1.82]	1.22 [0.81–1.48]	2.01 [1.34–3.01]	1.53 [0.94–2.49]	1.74 [1.11–2.71]	1.44 [0.86–2.41]	1.08 [0.78–1.51]	1.13 [0.81–1.60]
3rd Tertile (>10.07)	2.50 [1.38–4.52]	1.82 [0.93–3.55]	1.63 [0.81–3.31]	1.48 [0.66–3.33]	4.05 [1.81–9.08]	2.35 [0.89–6.18]	3.02 [1.24–7.36]	2.08 [0.75–5.79]	1.18 [0.61–2.28]	1.29 [0.65–2.55]
p	0.002	0.078	0.171	0.341	0.0006	0.082	0.014	0.158	0.629	0.466

AD Alzheimer’s disease, MCI mild cognitive impairment, MD mixed dementia, VaD vascular dementia, A not adjusted values, B values adjusted for age, sex, APOE ε4 allele, education