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. 2017 Apr 18;18(4):561–580. doi: 10.1007/s10522-017-9701-0

Table 5.

Univariate correlation analysis

Dementia (n = 205) Controls (n = 107)
Adiponectin Leptin Resistin Adiponectin Leptin Resistin
Age
 R 0.132 0.034 0.300 0.025 −0.064 0.294
 p value 0.059 0.633 0.00001 0.797 0.516 0.002
MMSE
 R −0.119 0.063 0.007
 p value 0.089 0.372 0.926
BMI
 R −0.519 0.644 0.014 −0.324 0.529 0.034
 p value <0.000001 <0.0000001 0.837 0.0007 <0.0000001 0.729
Glucose 0 h
 R −0.234 0.184 −0.003 −0.293 0.264 0.075
 p value 0.0007 0.008 0.971 0.002 0.006 0.442
Insulin
 R −0.360 0.402 −0.057 −0.409 0.228 0.084
 p value <0.000001 <0.0000001 0.415 0.00001 0.018 0.390
HOMA-IR
 R −0.402 0.415 −0.046 −0.457 0.278 0.099
 p value <0.000001 <0.000001 0.514 0.000001 0.004 0.309
IL-6
 R −0.187 0.153 0.340 −0.224 0.023 0.260
 p value 0.007 0.029 0.0000001 0.020 0.812 0.007
hsCRP
 R −0.170 0.314 0.234 −0.096 0.205 0.048
 p value 0.015 0.00004 0.0007 0.324 0.034 0.626
25-OH Vitamin D
 R 0.082 −0.085 −0.132 −0.027 −0.099 0.018
 p value 0.244 0.227 0.060 0.780 0.309 0.853
PON1
 R −0.024 0.042 −0.236 0.099 0.107 −0.166
 p value 0.727 0.545 0.0006 0.310 0.272 0.088
HDL-C
 R 0.499 −0.263 −0.301 0.311 0.025 0.094
 p value <0.0000001 0.0001 0.00001 0.001 0.801 0.334
Chitotriosidase
 R −0.035 0.077 0.165 0.125 0.125 −0.093
 p value 0.617 0.274 0.018 0.201 0.199 0.341

Spearman’s correlation coefficients (R) of adiponectin, leptin and resistin level with selected metabolic parameters and inflammation indices in dementia and controls

BMI body mass index, CRP C-reactive protein, HDL-C high density lipoprotein cholesterol, HOMA-IR homeostatic model assessment index, IL-6 interleukin 6, MMSE mini mental state examination, PON1 paraoxonase 1