Skip to main content
. 2016 Oct 20;2(1):62–84. doi: 10.1016/j.adro.2016.10.002

Variant 4.

A 60-y-old man, asymptomatic in PSA screening program

Treatment Rating Comments
Treatment planning
 IMRT (nonarc) 8 Dosimetry may be improved by avoiding beams that pass through prostheses.124, 128, 129
 VMAT (arc-based IMRT) 8 Dosimetry may be improved by using more arcs.137
 IMRT (helical tomotherapy) 7 This procedure has been previously described.138
 Proton beam 5 This procedure reflects recognized controversy in the field. Use anterior-oriented beams139 or oblique beams.140 CT simulation with kV and MV CT images improves range of uncertainties for planning.141
IGRT
 Radiofrequency transponders 7 Hip implants have no meaningful effect on image guidance with this strategy.135
 2D imaging with implanted fiducial markers 7
 MVCT/CBCT with fiducial markers 7
 Ultrasound 7 See reference134
Simulation
 CT simulation (kV CT) 8 Use a commercial algorithm to improve CT Hounsfield number accuracy and structure visualization.124, 125, 126
 Use MVCT to assist planning if available 7 This procedure may improve image resolution and permit calculation of electron density.131
 MRI simulation and fusion to CT 8 Bilateral hip implants are not a contraindication to CT/MRI simulation.133
 None 3
RT fractionation
 CFRT 8 This procedure is not a contraindication on previous protocol (ie, RTOG 940633).
 HFRT 6 This procedure is not a contraindication on previous protocol (ie, RTOG 0415149).
 SBRT 6 This procedure is not a contraindication on previous protocol (ie, RTOG 0938150).

Rating scale: 1, 2, 3 = usually not appropriate; 4, 5, 6 = may be appropriate; 7, 8, 9 = usually appropriate.

IGRT, image guidance radiation therapy; MVCT, megavoltage computed tomography; VMAT, volumetric modulated arc therapy. Other abbreviations as in Variants 1 and 3.

PSA 5.2 ng/mL, prostate without palpable abnormalities. Multiple needle biopsies of the prostate showed adenocarcinoma. Gleason score 3 + 3 = 6. Patient has bilateral hip implants.