Table 1.
Clinical and disease characteristics
| Characteristic | N | % |
|---|---|---|
| Age at recurrence, y | ||
| 40-50 | 3 | 25 |
| 50-60 | 3 | 25 |
| 60-70 | 3 | 25 |
| >70 | 3 | 25 |
| Primary site | ||
| Oropharynx | 5 | 42 |
| Nasopharynx | 4 | 33 |
| Oral cavity | 2 | 17 |
| Paranasal sinus | 1 | 8 |
| HPV status | ||
| Positive | 4 | 33 |
| Negative | 2 | 17 |
| Unknown | 6 | 50 |
| Smoking history | ||
| None | 4 | 33 |
| Yes, <10 packs/year | 1 | 8 |
| Yes, 10-40 packs/year | 3 | 25 |
| Yes, >40 packs/year | 4 | 33 |
| Sex | ||
| Male | 9 | 75 |
| Female | 3 | 25 |
| Karnofsky performance status | ||
| 90 | 3 | 25 |
| 80 | 5 | 42 |
| 70 | 4 | 33 |
| Ethnicity | ||
| White | 8 | 67 |
| Asian | 4 | 33 |
| Radiation therapy technique | ||
| SBRT | 6 | 50 |
| IMRT | 6 | 50 |
| Dose per fraction | ||
| 2 Gy | 6 | 50 |
| >2 Gy | 6 | 50 |
| Time from initial course of radiation therapy | ||
| <1 y | 6 | 50 |
| >1 y | 6 | 50 |
| Concurrent chemotherapy | ||
| Yes | 2 | 17 |
| No | 10 | 83 |
HPV, human papillomavirus; IMRT, intensity modulated radiation therapy; SBRT, stereotactic body radiation therapy.