Figure 1. Reduction of outer nuclear layer thickness after light exposure.

A: Retinas were fixed by 4% PFA, sectioned and stained with HE. Normal retina was well-organized; B, C: Compare to the normal control, the thickness of outer nuclear layers in light damaged groups were significant thinner (P<0.01); C: Additionally, some giant vacuoles can be seen in 8-hour-light exposure group (green arrows); D: The average thickness of outer nuclear layer (ONL) showed a dose dependent decrease manner. ^aP<0.05, ^bP<0.01, ^cP<0.001.