Efficient approach to correct read alignment for pseudogene abundance estimates

. Author manuscript; available in PMC: 2017 Jul 18.

Published in final edited form as: IEEE/ACM Trans Comput Biol Bioinform. 2016 Jul 14;14(3):522–533. doi: 10.1109/TCBB.2016.2591533

Input: {s₁, s₂, …, s_m} = a vector of read count for locus j, where 1 < j < m.

Output:

{{\hat{y}}_{1}, {\hat{y}}_{2}, \dots, {\hat{y}}_{n}}

¹ = a vector of estimated read count for gene i, where 1 < i < n.