Table 5.
Prediction performance of the kNN ensemble classifier with majority vote technique. The ensemble system predicts a drug-target pair to be interacting if all of kNN classifiers in the ensemble predict it to be interacting.
| Dataset | Target type | Rec | Acc | Prec | F1 |
|---|---|---|---|---|---|
| Test‡ | Enzymes | 0.779 | 0.918 | 0.972 | 0.864 |
| Ion channels | 0.906 | 0.882 | 0.778 | 0.837 | |
| GPCRs | 0.985 | 0.863 | 0.712 | 0.827 | |
| Nuclear receptors | 0.916 | 0.921 | 0.856 | 0.885 |
‡Prediction on the test dataset ℵts.