Table 5. Univariate associations between echo predictors and 180-day mortality.
Echocardiographic parameter | Hazard ratio (95% CI) | p-value |
Heart rate | ||
≤ 80 bpm, per change of 5 | 0.90 (0.76–1.06) | 0.0001 |
> 80 bpm, per change of 5 | 1.25 (1.03–1.52) | |
LVEDD (mm) | 1.01 (0.99–1.02) | 0.39 |
LVESD (mm) | 1.01 (0.99–1.02) | 0.38 |
IVSTd (mm) | 0.94 (0.89–0.99) | 0.025 |
PWTd (mm) | ||
≤ 9 mm | 0.77 (0.67–0.89) | 0.0009 |
> 9 mm | 1.32 (1.08–1.61) | |
LV mass | 1.00 (1.00–1.00) | 0.22 |
LVEF (%), per 5% increment | 0.96 (0.91–1.01) | 0.12 |
Left atrial size (A-P) (mm) | 1.00 (0.98–1.01) | 0.64 |
Left atrial size (planimetry) mm2 | 1.00 (1.00–1.00) | 0.50 |
E/A ratio, per doubling | 1.13 (0.92–1.39) | 0.23 |
E-wave deceleration time (ms) | 1.00 (0.99–1.00) | 0.07 |
MV A-wave duration | 1.00 (1.00–1.01) | 0.61 |
MV E/A ratio grades | ||
Grade 1: impaired relaxation | (reference group) | |
Grade 2: pseudonormal | 1.77 (0.92–3.38) | 0.19 |
Grade 3: restrictive filling | 1.67 (0.92–3.03) | |
Aortic stenosis | ||
None, mild | (reference group) | 0.039 |
Moderate | 3.60 (1.33– 9.74) | |
Severe | 0.83 (0.21–3.36) | |
Aortic regurgitation | ||
None, mild | (reference group) | 0.096 |
Moderate | 0.93 (0.46–1.90) | |
Severe | 2.30 (1.07–4.92) | |
Mitral stenosis | ||
None, mild | (reference group) | 0.89 |
Moderate | 0.99 (0.31–3.10) | |
Severe | 0.79(0.29-2.12) | |
Mitral regurgitation | ||
None, mild | (reference group) | 0.87 |
Moderate | 0.92 (0.62–1.34) | |
Severe | 1.05 (0.63–1.74) | |
Tricuspid regurgitation | ||
None, mild | (reference group) | 0.53 |
Moderate | 1.26 (0.85–1.86) | |
Severe | 1.04 (0.57–1.89) |
LVEDD, left ventricular end-diastolic diameter; LVESD, left ventricular end-systolic diameter; IVSTd, interventricular septal thickness in diastole; PWTd, posterior wall thickness in diastole; LV, left ventricular; LVEF, left ventricular ejection fraction; A-P, antero-posterior; MV, mitral valve. Heart rates are for an increment of one unit in the predictor unless otherwise noted.