Tumor-infiltrating lymphocytes. Tumor-infiltrating lymphocytes assayed from tumors of mice treated with (R) or (S)-DOTAP/E7 a CD4+ and CD8+ cells b CD4+ or CD8+ cells per 10,000 cells in the solid tumor. n = 3–4. When comparing (R)-DOTAP to (S)-DOTAP or tumor only, P < 0.01 for CD8+ cells; however, (S)-DOTAP compared to tumor alone, P = 0.57. Looking at the groups with regard to CD4+ cells, all comparisons yield P values greater than 0.3