Table 1.
Physical properties of the vaccine formulations
Formulation | Particle size (nm)* | Zeta potential (mV)** | Encapsulation efficiency (%)*** |
---|---|---|---|
R-DOTAP/E7 | 126.8 ± 5.1 | 54.3 ± 4.0 | 31.3 ± 16.6 |
S-DOTAP/E7 | 125.6 ± 7.8 | 55.8 ± 1.9 | 32.1 ± 8.9 |
Lipid concentration used in these studies was 6 mM, equivalent to 300 nmol of lipid per mouse
* P = 0.69, n = 8–10
** P = 0.37, n = 8–10
*** P = 0.87, n = 13–14