Table 4.
Univariate Associations Between Quality of Life End-points 6 mo After Surgery
| Variable | Outcome Measure | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Physical score | Mental score | IADL | ||||
|
|
|
|
||||
| Correlation or mean ± SE | P | Correlation or mean ± SE | P [R] | Correlation or mean ± SE | P [R] | |
| Age | r = −0.073 | 0.471 | r = −0.122 | 0.229 | r = −0.114 | 0.261 |
| Group | ||||||
| Placebo | 44 ± 1.4 | 0.509 | 44 ± 0.3 | 0.002 | 25 ± 0.4 | 0.822 |
| Estradiol | 43 ± 1.6 | 43 ± 0.4 | 25 ± 0.4 | |||
| Race | ||||||
| Caucasian | 44 ± 1.1 | 0.544 | 44 ± 0.3 | 0.886 | 25 ± 0.3 | 0.712 |
| African American | 39 ± 3.2 | 44 ± 0.7 | 24 ± 0.9 | |||
| History CVA | ||||||
| No | 44 ± 1.1 | 0.273 | 44 ± 0.3 | 0.148 | 25 ± 0.3 | 0.314 |
| Yes | 40 ± 3.2 | 45 ± 0.7 | 24 ± 0.9 | |||
| History TIA | ||||||
| No | 44 ± 1.1 | 0.645 | 44 ± 0.2 | 0.675 | 25 ± 0.3 | 0.087 |
| Yes | 41 ± 4.7 | 43 ± 1.1 | 23 ± 1.3 | |||
| COPD | ||||||
| No | 43 ± 1.1 | 0.842 | 44 ± 0.3 | 0.376 | 25 ± 0.3 | 0.751 |
| Yes | 44 ± 3.1 | 43 ± 0.7 | 25 ± 0.8 | |||
| CHF | ||||||
| No | 43 ± 1.1 | 0.612 | 43 ± 0.3 | 0.172 | 25 ± 0.3 | 0.870 |
| Yes | 45 ± 2.5 | 44 ± 0.6 | 25 ± 0.7 | |||
| LV function | ||||||
| Normal | 44 ± 1.3 | 0.287 | 44 ± 0.3 | 0.104 | 25 ± 0.4 | 0.654 |
| Mild reduced | 41 ± 2.5 | 43 ± 0.6 | 24 ± 0.7 | |||
| Moderately reduced | 49 ± 3.8 | 42 ± 0.9 | 25 ± 1.1 | |||
| Severely reduced | 42 ± 4.4 | 45 ± 1.0 | 25 ± 1.2 | |||
| Hypertension | ||||||
| No | 45 ± 2.6 | 0.547 | 44 ± 0.6 | 0.856 | 26 ± 0.7 | 0.319 |
| Yes | 43 ± 1.1 | 44 ± 0.3 | 25 ± 0.3 | |||
| Previous MI | ||||||
| No | 44 ± 1.3 | 0.460 | 44 ± 0.3 | 0.752 | 25 ± 0.4 | 0.528 |
| Yes | 42 ± 1.7 | 44 ± 0.4 | 25 ± 0.5 | |||
| PVD | ||||||
| No | 45 ± 1.1 | 0.012 | 44 ± 0.3 | 0.535 | 25 ± 0.3 | 0.272 |
| Yes | 37 ± 2.6 | 43 ± 0.6 | 24 ± 0.7 | |||
| Type I Diabetes | ||||||
| No | 44 ± 1.1 | 0.097 | 43 ± 0.3 | 0.106 | 25 ± 0.3 | 0.755 |
| Yes | 40 ± 2.6 | 45 ± 0.6 | 25 ± 0.7 | |||
| Type II Diabetes | ||||||
| No | 44 ± 1.2 | 0.166 | 44 ± 0.3 | 0.405 | 25 ± 0.3 | 0.122 |
| Yes | 41 ± 2.0 | 44 ± 0.5 | 24 ± 0.5 | |||
| Smoking | ||||||
| Never | 44 ± 1.4 | 0.636 | 43 ± 0.3 | 0.017 | 25 ± 0.4 | 0.485 |
| Current | 41 ± 2.7 | 43 ± 0.6 | 24 ± 0.7 | |||
| Prior | 44 ± 2.0 | 45 ± 0.4 | 25 ± 0.5 | |||
| Postoperaitve No | 44 ± 1.1 | 0.448 | 44 ± 0.3 | 0.655 | 25 ± 0.3 | 0.896 |
| Atrial Fibrillation Yes | 42 ± 2.8 | 44 ± 0.6 | 24 ± 0.8 | |||
| Neurocognitive No | 47 ± 1.3 | 0.004 | 44 ± 0.4 | 0.936 | 26 ± 0.4 | 0.029 |
| Deficit Yes | 37 ± 3.3 | 44 ± 0.9 | 24 ± 1.1 | |||
| Log days in hospital | r = −0.041 | 0.686 | r = 0.054 | 0.598 | r = −0.118 | 0.245 |
| Log days in ICU | r = −106 | 0.295 | r = 0.093 | 0.358 | r = −0.200 | 0.047 |
| Beck depression index | r = −0.098 | 0.336 | r = −0.223 | 0.026 | r = −0.023 | 0.823 |
| Beck anxiety index | r = −0.041 | 0.685 | r = −0.099 | 0.332 | r = 0.113 | 0.264 |
All P-values are adjusted for the baseline value of the outcome measure. Entries are baseline-adjusted partial correlation coefficient between continuous predictors and outcomes and baseline-adjusted least square means ± SE of categorical predictors.
CVA = cerebrovascular accident; COPD = chronic obstructive pulmonary disease; CHF = congestive heart failure; LV = left ventricular; MI = myocardial infarction; PVD = peripheral vascular disease; ICU = intensive care unit; IADL = Lawton instrumental activities of daily living scale.