Table 2.
The virologic responses in both groups.
| Response | Fixed 12 weeks (Ref.) | Response-tailored (test) | Proportion difference (Ref-test) | Z | P (2-tail) |
|---|---|---|---|---|---|
| vRVR (ITT) | 49/60 (81.67%) (CI: 70.08–89.44%) | 48/60 (80%) (CI: 68.22–88.17%) | 1.67%) (CI: − 12.51–+15.78%) | 0.232 | 0.817 |
| SVR12 (ITT) | 58/60 (96.67%) (CI: 88.64–99%) | 59/60 (98.33%) (CI: 91.14–99.71%) | (− 1.67%) (CI: − 9.8%–+5.9%) | 0.6 | 0.569 |
| SVR12 (PP) | 58/59 (98.31%) (CI: 91–99.7%) | 59/59 (100%) (CI: 93.89–100%) | (− 1.69%) (CI: − 9%–+4.58%) | 1 | 0.315 |
| SVR12/8w (ITT) | 47/48 (97.92%) (CI: 89.1–99.6%) | ||||
| SVR12/8w (PP) | 47/47 (100%) (CI: 92.4–100%) |
vRVR (very rapid virologic response at week 2).
SVR12 (sustained virologic response at 12 weeks post-treatment).
SVR12/8w (sustained virologic response at 12 weeks after the end of 8 weeks-treatment course).
Data are n/N (%) (95% Confidence Interval (CI:) by Wilson score method).
ITT (Intention-to-treat population); PP (Per Protocol analysis for those who completed the full protocol).