Table 2.
Characteristics of included patients.
| Age at diagnosis |
|||||
|---|---|---|---|---|---|
| Characteristic | Total | A1 (≤ 16) | A2 (17–40) | A3 (> 40) | p-value |
| Total (N) | 627 | 91 | 426 | 110 | |
| City | |||||
| Calgary | 324 (52%) | 45 (49%) | 218 (51%) | 61 (55%) | 0.87 |
| Edmonton | 303 (48%) | 46 (51%) | 208 (49%) | 49 (45%) | |
| Sex | |||||
| Male | 260 (41%) | 50 (55%) | 155 (36%) | 55 (50%) | 0.68 |
| Female | 367 (59%) | 41 (45%) | 271 (64%) | 55 (50%) | |
| NOD2 (1007fs), N (%) | |||||
| Wild type | 558 (89%) | 77 (85%) | 374 (88%) | 107 (97%) | 0.003 |
| Carriera | 69 (11%) | 14 (15%) | 52 (12%) | 3 (3%) | |
| Smoking status, N (%) | |||||
| Ever | 285 (46%) | 4 (4%) | 203 (48%) | 78 (71%) | < 0.0001 |
| Never | 342 (54%) | 87 (96%) | 223 (52%) | 32 (29%) | |
Abbreviations: Q1: 1st quartile (25th percentile); Q3: 3rd quartile (75th percentile).
a
Carriers of the 1007 fs variant (heterozygous or homozygous) were compared to wild type.