Table 1D.
Hemodynamic parameters EDC treatment in csERagr;-WT and cs-ERα-KO
| Heart samples | Pre-ischemic equilibration | Post-ischemic/End of reperfusion | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
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| (n) | Body weight (g) | FR (ml/min) | HR (bpm) | LVDP (cmH2O) | FR (ml/min) | HR (bpm) | LVDP (cmH2O) | |
| cs-ERαWT | 8 | 24±1 | 2.4±0.3 | 376±25 | 144±11 | 1.7±0.1 | 328±17 | 57±6# |
| cs-ERαWT + EDC | 9 | 23±1 | 2.9±0.3 | 377±17 | 143±6 | 1.9±0.1 | 339±9 | 77±4 |
| cs-ERαKO | 5 | 21±1 | 2.5±0.2 | 388±23 | 148±10 | 1.8±0.1 | 325±20 | 67±9# |
| cs-ERαKO + EDC | 7 | 22±1 | 2.8±0.3 | 375±24 | 135±9 | 1.8±0.1 | 336±20 | 98±7 |
Values are mean ± SE; (n), number of hearts; FR, flow rate (ml/min); HR, heart rate (beats per min, bpm); LVDP, left ventricular developed pressure.
p<0.05 vs the same genotype + EDC.