Table 1E.
Hemodynamic parameters EDC treatment in esERα-WT and -KO
| Heart samples | Pre-ischemic equilibration | Post-ischemic/End of reperfusion | ||||||
|---|---|---|---|---|---|---|---|---|
|
|
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| (n) | Body weight (g) | FR (ml/min) | HR (bpm) | LVDP (cmH2O) | FR (ml/min) | HR (bpm) | LVDP (cmH2O) | |
| es-ERαWT | 5 | 23±0.3 | 2.2±0.1 | 365±5.3 | 138±3 | 1.7±0.1 | 294±9 | 49±4# |
| es-ERαWT + EDC | 6 | 22±0.5 | 2.2±0.1 | 355±17 | 121±9 | 1.6±0.01 | 329±21 | 62±4 |
| es-ERαKO | 6 | 23±0.8 | 2.0±0.1 | 344±16 | 129±8 | 1.6±0.1 | 302±6 | 41±2 |
| es-ERαKO + EDC | 7 | 23±0.5 | 2.1±0.1 | 375±11 | 125±7 | 1.6±0.1 | 304±13 | 47±4 |
Values are mean ± SE; (n), number of hearts; FR, flow rate (ml/min); HR, heart rate (beats per min, bpm); LVDP, left ventricular developed pressure.
p<0.05 vs the same genotype + EDC.