Table 3.

Adjusted Means and Adjusted Mean Changes in Follow-up Measures of Retrospective Memory (WRAML2) for Specific HIV Disease Severity Measures^* in Youth with PHIV

		Adjusted Results
Disease Severity Measure	Covariate/Level	Mean (95% CI) or Estimate (SE)	P-Value
Verbal Learning 1,2,3
Positive Change in CD4%	(continuous)	−0.08 (0.03)	0.01
Verbal Delay Recall 1,2,4
CD4% ≥ 25% at entry	≥ 25%	9.45 (8.94,9.96)	0.05
	< 25%	8.60 (7.80,9.40)
Verbal Recognition 2,5
CD4% ≥ 25% at entry	≥ 25%	9.94 (9.45, 10.44)	0.001
	< 25%	8.45 (7.65, 9.24)
Log HIV RNA VL at entry	(continuous)	−0.50 (0.21)	0.02
Design Memory 2,6
Age at CDC Class C	0 – 3 years	7.63 (6.71, 8.56)	0.01
	> 3 years	9.83 (8.06, 11.60)
	PHIV/non-C status	9.14 (8.60, 9.69)

Note. *Table includes only those HIV disease severity measures with significant differences in adjusted means (categorical covariates) or significant regression coefficients (continuous measures). The adjusted mean and 95% CI are provided for each level of categorical covariates. For continuous covariates, the adjusted mean change (and standard error) in outcome for each one-unit change in predictor is presented. Adjusted models included the following covariates: 1-Black race; 2-age at Memory/EF entry; 3-annual household income > $20,000; 4-male sex; 5-caregiver is high school graduate; 6-caregiver is biological parent. PHIV/non-C: perinatally acquired HIV, without CDC Class C diagnosis; VL: viral load.