FIG 12.

CDDO-Im treatment partially inhibits activation of T cells in Sf mice. (A) Frequencies of T cell populations in the LNs of vehicle-treated WT (n = 5), CDDO-Im-treated WT (n = 4), vehicle-treated Sf (n = 7), and CDDO-Im-treated Sf (n = 7) mice. Percentages of CD4 and CD8 single-positive cells in LN cells (left) and percentages of CD25⁺, CD44⁺, and CD69⁺ cells in CD4 single-positive cells (right) are shown. The values indicate the means and SD. (B) Representative histogram data for CD4 single-positive LN cells from WT and Sf mice treated with vehicle or CDDO-Im, along with percentages of CD25⁺, CD44⁺, and CD69⁺ cells. *, P < 0.05; ***, P < 0.0005.