TABLE 1.
Peripheral blood analysis of Sf::Keap1FA/− micea
| Parameter | Valueb for: |
P value |
|||
|---|---|---|---|---|---|
| WT mice | Sf mice | Sf::Keap1FA/− mice | WT vs Sf mice | Sf vs Sf::Keap1FA/− mice | |
| WBC count (102/μl) | 60 ± 18 | 61 ± 25 | 48 ± 16 | NS | NS |
| RBC count (104/μl) | 513 ± 117 | 374 ± 60 | 495 ± 102 | <0.005 | <0.005 |
| Hb concn (g/dl) | 7.2 ± 1.5 | 5.4 ± 1.0 | 7.0 ± 1.3 | <0.006 | <0.007 |
| Hct (%) | 24.2 ± 5.9 | 18.7 ± 2.8 | 26.3 ± 5.8 | <0.05 | <0.007 |
| MCV (fl) | 47.1 ± 2.4 | 50.2 ± 1.1 | 50.4 ± 1.5 | <0.02 | NS |
| MCH level (pg) | 14.2 ± 1.3 | 14.5 ± 1.5 | 14.3 ± 0.8 | NS | NS |
| MCHC (g/dl) | 30.1 ± 2.1 | 28.9 ± 2.6 | 28.3 ± 1.7 | NS | NS |
| PLT count (104/μl) | 108 ± 31 | 82 ± 17 | 143 ± 42 | <0.04 | <0.004 |
a
WBC, white blood cell; RBC, red blood cell; Hb, hemoglobin; Hct, hematocrit; MCV, mean corpuscular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; PLT, platelet; NS, not significant.
b
Values are presented as the means ± SD for WT (n = 7), Sf (n = 11), and Sf::Keap1FA/− (n = 8) mice.