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. 2017 Jul 17;22:12. doi: 10.1186/s11658-017-0041-5

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The effect of miR-378 on the migration and invasion abilities of colon cancer cells. a, b The effect of miR-378 mimics on the migration (a) and invasion (b) of SW480 and HCT-116 cells determined using Transwell plates. c Quantitative RT-PCR was used to measure the mRNA levels of three EMT markers, e-Cadherin, vimentin and a-SMA, in miR-378 mimics transfected SW480 cells. d Western blot was used to measure the protein levels of these EMT makers in SW480 cells transfected with miR-378 mimics. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001