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. 2017 Jul 17;16:123. doi: 10.1186/s12943-017-0702-z

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — miR-367 promoted migration, invasion and EMT process of HCC cells. a miR-367 silencing restrained migration and invasion of MHCC-97H cells. b The number migrated and invaded Hep-3B cells were increased after miR-367 restoration. c Immunohistochemistry analysis (magnification: ×400; Scale bar:100 μm) showed that HCC tissues in high miR-367 group presented lower E-cadherin expression and higher Vimentin expression compared to those in low miR-367 group. d miR-367 knockdown significantly increase E-cadherin expression and decrease Vimentin expression in MHCC-97H cells. e miR-367 overexpression facilitated EMT progression of Hep-3B cells. *P < 0.05, **P < 0.01