. 2017 Jul 17;16:123. doi: 10.1186/s12943-017-0702-z

Table 1.

Correlation between the clinicopathologic characteristics and CASC2 and miR-367 expression in HCC (n = 75)

Clinical parameters	Cases	Expression level		P value	Expression level		P value
Clinical parameters	Cases	CASC2^high (n = 38)	CASC2^low (n = 37)	P value	miR-367^high (n = 38)	miR-367^low (n = 37)	P value
Age(years)
< 50	24	13	11	0.677	10	14	0.285
≥ 50	51	25	26	0.677	28	23	0.285
Gender
Male	64	34	30	0.304	32	32	0.781
Female	11	4	7	0.304	6	5	0.781
HBV
Absent	13	9	4	0.141	7	6	0.801
Present	62	29	33	0.141	31	31	0.801
Serum AFP level (ng/mL)
< 400	18	11	7	0.127	6	12	0.092
≥ 400	57	27	30	0.127	32	25	0.092
Tumor size (cm)
< 5	34	21	13	0.080	12	22	0.015^a
≥ 5	41	17	24	0.080	26	15	0.015^a
Number of tumor nodules
1	62	35	28	0.104	30	32	0.389
≥ 2	13	4	9	0.104	8	5	0.389
Cirrhosis
Absent	20	12	8	0.330	7	13	0.102
Present	55	26	29	0.330	31	24	0.102
Venous infiltration
Absent	54	33	21	0.004^a	23	31	0.025^a
Present	21	5	16	0.004^a	15	6	0.025^a
Edmondson-Steiner grading
I + II	49	29	20	0.043^a	22	27	0.170
III + IV	26	9	17	0.043^a	16	10	0.170
TNM tumor stage
I + II	56	34	22	0.003^a	24	32	0.020^a
III + IV	19	4	15	0.003^a	14	5	0.020^a

HCC hepatocellular carcinoma, HBV hepatitis B virus, AFP alpha-fetoprotein, TNM tumor-node-metastasis

^aStatistically significant